Zainteresowania

• biochemistry molecular biology
• golgi
• glycosylation
• n glycosylation
• n glycans
• golgi apparatus
• nucleotide sugar transporters
• slc35a2
• nucleotide sugar transporter
• udp galactose

Dyscyplina naukowa

• biotechnologia

Najnowsze publikacje

• SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization
• Delivery of Nucleotide Sugars to the Mammalian Golgi: A Very Well (un) Explained Story
• Novel Insights into Selected Disease-Causing Mutations within the SLC35A1 Gene Encoding the CMP-Sialic Acid Transporter
• The glycosylation defect in solute carrier SLC35A2/SLC35A3 double knockout cells is rescued by SLC35A2–SLC35A3 and SLC35A3–SLC35A2 hybrids
• SLC35A2 Deficiency Promotes an Epithelial-to-Mesenchymal Transition-like Phenotype in Madin–Darby Canine Kidney Cells
• Identification of novel potential interaction partners of UDP-galactose (SLC35A2), UDP-N-acetylglucosamine (SLC35A3) and an orphan (SLC35A4) nucleotide sugar transporters
• An interaction between SLC35A1 and ST3Gal4 is differentially affected by CDG-causing mutations in the SLC35A1 gene
• Incorporation of fucose into glycans independent of the GDP-fucose transporter SLC35C1 preferentially utilizes salvaged over de novo GDP-fucose
• Demonstration of Heterologous Complexes formed by Golgi-Resident Type III Membrane Proteins using Split Luciferase Complementation Assay
• N-glycosylation of the human β1,4-galactosyltransferase 4 is crucial for its activity and Golgi localization
• Analysis of homologous and heterologous interactions between UDP-galactose transporter and beta-1,4-galactosyltransferase 1 using NanoBiT