Interested

• biochemistry molecular biology
• developmental biology
• plant biology botany
• oncology carcinogenesis

Scientific discipline

• medical sciences

Latest publications

• HIF-1-induced hsa-miR-429: understanding its direct targets as the key to developing cancer diagnostics and therapies
• The unfolded protein response: a double-edged sword for brain health
• Ubiquitin-dependent and independent proteasomal degradation in host-pathogen interactions
• The lipid side of unfolded protein response
• The role of the hypoxia-related unfolded protein response (UPR) in the tumor microenvironment
• Plasma untargeted metabolomics with proteinase K discloses phospholipid signature associated with pulmonary arterial hypertension
• IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A
• Utilizing genome-wide mRNA profiling to identify the cytotoxic chemotherapeutic Mechanism of triazoloacridone C-1305 as direct microtubule stabilization.
• VDR and PDIA3 are essential for activation of calcium signaling and membrane response to 1,25(OH)₂D₃ in squamous cell carcinoma cells
• Editorial focus: understanding off-target effects as the key to successful RNAi therapy.
• The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability
• Regulation of the HIF switch in human endothelial and cancer cells
• A rare mutation (p.F149del) of the NT5C3A gene is associated with pyrimidine 5′-nucleotidase deficiency
• Efficient method for isolation of reticulocyte RNA from healthy individuals and hemolytic anaemia patients.
• Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice
• EPAS1 resistance to miRNA-based regulation contributes to prolonged expression of HIF-2 during hypoxia in human endothelial cells
• Dual RNase activity of IRE1 as a target for anticancer therapies
• Chloroplast PetD protein: evidence for SRP/Alb3-dependent insertion into the thylakoid membrane.
• miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells.
• microRNA single polynucleotide polymorphism influences on microRNA biogenesis and mRNA target specificity.