Interested

• biochemistry molecular biology
• general science technology
• developmental biology
• chemical physics
• oncology carcinogenesis

Scientific discipline

• medical sciences
• biological sciences

Latest publications

• Integrin-linked kinase (ILK) plays an important role in the laminin-dependent development of dorsal root ganglia during chicken embryogenesis.
• Changes in biomechanical properties of A375 cells due to the silencing of TMSB4X expression are not directly correlated with alterations in their stemness features.
• ABCA1 transporter promotes the motility of human melanoma cells by modulating their plasma membrane organization
• Gelsolin contributes to the motility of A375 melanoma cells and this activity is mediated by the fibrous extracellular matrix protein profile.
• Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) technique shows that non-muscle β and γ actin are not equal in relation to human melanoma cells’ motility and focal adhesion formation.
• The origin of the expressed retrotransposed gene ACTBL2 and its influence on human melanoma cells’ motility and focal adhesion formation.
• Integrin-linked kinase (ILK): the known vs. the unknown and perspectives
• SLC35A2 Deficiency Promotes an Epithelial-to-Mesenchymal Transition-like Phenotype in Madin–Darby Canine Kidney Cells
• The role of non-muscle actin paralogs in cell cycle progression and proliferation
• Thymosin β4 regulates focal adhesion formation in human melanoma cells and affects their migration and invasion.
• Integration of cardiac actin mutants causing hypertrophic (p.A295S) and dilated cardiomyopathy (p.R312H and p.E361G) into cellular structures.
• Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs)
• Isolation of stably transfected melanoma cell clones
• Gelatin zymography to detect gelatinase activity in melanoma cells
• A fluorescent gelatin degradation assay to study melanoma breakdown of extracellular matrix.
• Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines.
• Involvement of β- and γ-actin isoforms in actin cytoskeleton organization and migration abilities of bleb-forming human colon cancer cells.
• Are non-muscle actin isoforms functionally equivalent?