Interested

• biochemistry molecular biology
• signaling
• chemical physics
• fgf
• fgfr
• fgf12
• fgfs
• fhfs
• protein–protein interaction
• protein protein interaction

Scientific discipline

• biomedical engineering
• biotechnology

Latest publications

• FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner.
• Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
• Low stability of integrin-binding deficient mutant of FGF1 restricts its biological activity.
• Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation
• Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling
• FGF homologous factors are secreted from cells to induce FGFR‐mediated anti‐apoptotic response
• FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex
• Galectins use N-glycans of FGFs to capture growth factors at the cell surface and fine-tune their signaling
• Stability and resistance to proteolysis of enterotoxins SEC and SEL produced by Staphylococcus epidermidis and Staphylococcus aureus
• High affinity promotes internalization of engineered antibodies targeting FGFR1.
• A conjugate based on anti-HER2 diaffibody and auristatin E targets HER2-positive cancer cells
• Translocation of exogenous FGF1 and FGF2 protects the cell against apoptosis independently of receptor activation
• Cytotoxic conjugates of fibroblast growth factor 2 (FGF2) with monomethyl auristatin E for effective killing of cells expressing FGF receptors.