Interested

• biochemistry molecular biology
• melanoma
• general science technology
• adipocytes
• tumor microenvironment
• cancer associated adipocytes
• cancer‑associated adipocytes
• cancer associated adipocytes caas
• targeted therapy
• tumor microenvironment tme

Scientific discipline

• medical sciences
• biotechnology

Latest publications

• Mutual impact of adipocytes and colorectal cancer cells growing in co-culture conditions
• Changes in biomechanical properties of A375 cells due to the silencing of TMSB4X expression are not directly correlated with alterations in their stemness features.
• Gelsolin contributes to the motility of A375 melanoma cells and this activity is mediated by the fibrous extracellular matrix protein profile.
• PARP1 as a marker of an aggressive clinical phenotype in cutaneous melanoma - a clinical and an in vitro study.
• Evaluation of apelin and apelin receptor level in the primary tumor and serum of colorectal cancer patients.
• The impact of cellular elements of TME on melanoma biology and its sensitivity to EGFR and MET targeted therapy
• Characterization of Melanoma Cell Lines Resistant to Vemurafenib and Evaluation of Their Responsiveness to EGFR- and MET-Inhibitor Treatment
• Melanoma Progression under Obesity: Focus on Adipokines
• Melanoma stimulates the proteolytic activity of HaCaT keratinocytes
• The Influence of Tumor Microenvironment on Immune Escape of Melanoma
• Hypoxia and Extracellular Acidification as Drivers of Melanoma Progression and Drug Resistance
• Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts
• Stromal Cells Present in the Melanoma Niche Affect Tumor Invasiveness and Its Resistance to Therapy
• Melanoma cells induce dedifferentiation and metabolic changes in adipocytes present in the tumor niche
• Combination of selected MET and EGFR inhibitors decreases melanoma cells’ invasive abilities.
• Expression level of EGFR and MET receptors regulates invasiveness of melanoma cells.
• Thymosin β4 regulates focal adhesion formation in human melanoma cells and affects their migration and invasion.
• The two faces of platinum hydrospirophosphorane complexes. Not only relevant catalysts but cytotoxic compounds as well.
• Combinations of EGFR and MET inhibitors reduce proliferation and invasiveness of mucosal melanoma cells
• Alpha-Enolase (ENO1) correlates with invasiveness of cutaneous melanoma - an in vitro and a clinical study.