Interested

• biochemistry molecular biology
• analytical chemistry
• organic chemistry
• fluorescence
• inorganic nuclear chemistry
• medicinal biomolecular chemistry
• modification
• mixtures
• peptides and proteins probes

Scientific discipline

• biomedical engineering

Latest publications

• Direct interaction of ATP7B and LC3B proteins suggests a cooperative role of copper transportation and autophagy.
• From methodological limitations to the function of metallothioneins - a guide to approaches for determining weak, moderate, and tight affinity zinc sites
• Molecularly imprinted polymers coupled to mass spectrometric detection for metallothionein sensing.
• Biarsenical fluorescent probes for multifunctional site-specific modification of proteins applicable in life sciences: an overview and future outlook.
• Biarsenical-based fluorescent labeling of metallothioneins as a method for ultrasensitive quantification of poly-Cys targets
• The connection of α- and β-domains in mammalian metallothionein-2 differentiates Zn(II) binding affinities, affects folding, and determines zinc buffering properties
• Investigation of metal ion binding biomolecules one molecule at a time
• Site-Specific and Fluorescently Enhanced Installation of Post-Translational Protein Modifications via Bifunctional Biarsenical Linker
• Short-sweep capillary electrophoresis with a selective zinc fluorescence imaging reagent FluoZin-3 for determination of free and metalothionein-2a-bound Zn2+ ions.
• Cu transfer from amyloid-β_4–16 to metallothionein-3: the role of the neurotransmitter glutamate and metallothionein-3 Zn(II)-load states.
• Fluorescent probes for selective protein labeling in lysosomes: a case of α-galactosidase A
• Molar absorption coefficients and stability constants of Zincon metal complexes for determination of metal ions and bioinorganic applications.
• Optimized allosteric inhibition of engineered protein tyrosine phosphatases with an expanded palette of biarsenical small molecules